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Carcinogenesis Inside a life span carcinogenicity research carried out in B6C3F1 mice, methylphenidate prompted a rise in hepatocellular adenomas, and in males only, a rise in hepatoblastomas at a everyday dose of about 60 mg/kg/working day. This dose is close to 2 instances the MRHD of sixty mg/working day presented to youngsters on mg/m2 basis.Te